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September 27, 2007

Allure Magazine Names RELASTIN(TM) Eye Silk(TM) 'Best Anti-Wrinkle Eye Cream' of 2007


NEW YORK, Sept. 27 /PRNewswire/ -- Revance Therapeutics Inc. announced that its RELASTIN Eye Silk product has received Allure magazine's "Best in Beauty" award for the best anti-wrinkle eye cream. Unveiled in Allure's October 2007 issue, winners represent the very best new beauty products as chosen by the magazine's editorial staff. Revance Therapeutics, a biopharmaceutical company that is pioneering transdermal delivery of biologically active macromolecules, is best known for its flagship product, currently in clinical development - a gel-based, needle-free, topically delivered botulinum neurotoxin type A.

Revance Therapeutics's RELASTIN over-the-counter (OTC) product line, including the award-winning Eye Silk product, represents a scientific breakthrough in anti-aging technologies. "Revance's focus on science and clinical results led to the discovery of the unique Zinc Firming Complex featured in RELASTIN Eye Silk. Our proprietary technology is the first to clinically demonstrate increased elastin in the skin," said Dan Browne, President and Chief Executive Officer. "We are honored that Allure, the nation's preeminent source for the best picks in beauty, has honored RELASTIN's visible results, echoing the praise of dermatologists around the country and our RELASTIN consumers."

"I am pleased that Allure has celebrated the scientific results of RELASTIN," remarked Dr. Vic Narurkar, past president of the American Society of Cosmetic Dermatology and Aesthetic Surgery, and director of the Bay Area Laser Institute. "For the first time, we've seen a product that has scientific evidence to support the increase of the elastin content in the skin. RELASTIN has a three-dimensional impact on the skin; until now, I have only seen this type of impact from physician office treatments such as lasers and injectables. It is a breakthrough that RELASTIN, as an OTC product, can affect the skin on this level."

While many anti-aging products focus on collagen production, RELASTIN Eye Silk goes beyond this benefit and is intended to increase skin elasticity. Clinical research has demonstrated that Eye Silk's patent-pending Zinc Firming Complex works at the cellular level to help promote the formation of functional elastin, a protein fiber essential for skin elasticity, and to help augment hypodermal fat to improve skin contour. As skin ages, elastin fibers break down and weaken, causing the skin to lose firmness, sag and wrinkle. Clinical evidence has shown that RELASTIN Eye Silk may improve skin contour and prevent further degeneration of elastin content, and significantly decrease the appearance of existing fine lines and coarse wrinkles, under eye laxity, and puffiness.

The RELASTIN product line is available at the RELASTIN web site, www.skinstore.com and select dermatologist's offices nationwide. Additional information on RELASTIN can be found at www.relastin.com.

ABOUT RELASTIN

RELASTIN Eye Silk cream has been clinically proven to increase the production of elastin, a natural protein that gives the skin elasticity. RELASTIN penetrates the skin to work with the cells to promote the formation of elastin, which the body ceases producing at puberty. The RELASTIN line also includes an overall facial moisturizer, Skin Revitalizer, which has demonstrated some significant decrease in visible signs of aging in clinical research and testing. Additional RELASTIN products containing the exclusive Zinc Firming Complex will be launched in early 2008.

ABOUT REVANCE THERAPEUTICS, INC.

Revance Therapeutics is a specialty biopharmaceutical company whose mission is to develop and commercialize products using our novel Macromolecule Transport System (MTS) to carry a range of molecules across human skin. Our focus will be on targets to improve aesthetics and personal wellness.

Revance is developing its lead compound, a topical botulinum neurotoxin based on its pioneering MTS transdermal drug delivery platform and next generation, low molecular weight botulinum neurotoxin. The MTS technology is being designed and tested to improve tolerability by eliminating the need for needle injections, to permit a safe, local, targeted, and painless approach to treat facial aesthetics and hyperhidrosis.

RELASTIN, EYE SILK, and REVANCE are trademarks of Revance Therapeutics, Inc.

Website: http://www.relastin.com/
Website: http://www.skinstore.com/